
Inflammation is the response of living tissue to damage. The acute inflammatory response has 3 main functions:
- The affected area is occupied by a transient material called the acute inflammatory exudate. The exudate carries proteins, fluid and cells from local blood vessels into the damaged area to mediate local defenses
- If an infective causative agent (e.g. bacteria) is present in the damaged area, it can be destroyed and eliminated by components of the exudate.
- The damaged tissue can be broken down and partially liquefied, and the debris removed from the site of damage.
Causes of Inflammation
Causes of inflammation include the following:
- microbial infections – this is the most common from bacteria and virus
- Hypersensitivity or Allergic Reactions – arising from an altered state of immunological responsiveness that causes an inappropriate or excessive immune reaction damaging the tissues
- Physical agents – arising from physical trauma such as burns or frost bites
- Tissue Necrosis – due lack of oxygen or nutrients resulting from inadequate blood flow


Signs of Inflammation
Silent Inflammation
The most deadly type of inflammation is where there are no symptoms or physical signs. This is described by Dr Barry Sears as Silent Inflammation. He called it the Silent Killer in his book “The Anti-Inflammation Zone”. Such Inflammation causes aging, heart attack, stroke, cancer and many other health threats.

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